Bacterial Lysate from the Multi-Strain Probiotic SLAB51 Triggers Adaptative Responses to Hypoxia in Human Caco-2 Intestinal Epithelial Cells under Normoxic Conditions and Attenuates LPS-Induced Inflammatory Response

Hypoxia-inducible factor-1α (HIF-1α), a central player in maintaining gut-microbiota homeostasis, plays a pivotal role in inducing adaptive mechanisms to hypoxia and is negatively regulated by prolyl hydroxylase 2 (PHD2). HIF-1α is stabilized through PI3K/AKT signaling regardless of oxygen levels. C...

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Detalles Bibliográficos
Autores principales: Lombardi, Francesca, Augello, Francesca Rosaria, Palumbo, Paola, Bonfili, Laura, Artone, Serena, Altamura, Serena, Sheldon, Jenna Marie, Latella, Giovanni, Cifone, Maria Grazia, Eleuteri, Anna Maria, Cinque, Benedetta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10179068/
https://www.ncbi.nlm.nih.gov/pubmed/37175841
http://dx.doi.org/10.3390/ijms24098134

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10179068/
https://www.ncbi.nlm.nih.gov/pubmed/37175841
http://dx.doi.org/10.3390/ijms24098134

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