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Serelaxin Alleviates Fibrosis in Thyroid-Associated Ophthalmopathy via the Notch Pathway

Fibrosis is the late stage of thyroid-associated ophthalmopathy (TAO), resulting in serious complications. Effective therapeutic drugs are still lacking. We aimed to explore the mechanism of TAO fibrosis and to find a targeted drug. High-throughput RNA sequencing was performed on orbital connective...

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Detalles Bibliográficos
Autores principales: Sun, Anqi, Ye, Huijing, Xu, Zhihui, Chen, Jingqiao, Xiao, Wei, Zhang, Te, Sha, Xiaotong, Bi, Shaowei, Zhou, Tianyi, Yang, Huasheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10179109/
https://www.ncbi.nlm.nih.gov/pubmed/37176063
http://dx.doi.org/10.3390/ijms24098356