Rational Design of Daunorubicin C-14 Hydroxylase Based on the Understanding of Its Substrate-Binding Mechanism

Doxorubicin is one of the most widely used antitumor drugs and is currently produced via the chemical conversion method, which suffers from high production costs, complex product separation processes, and serious environmental pollution. Biocatalysis is considered a more efficient and environment-fr...

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Detalles Bibliográficos
Autores principales: Zhang, Jing, Gao, Ling-Xiao, Chen, Wei, Zhong, Jian-Jiang, Qian, Chao, Zhou, Wen-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10179135/
https://www.ncbi.nlm.nih.gov/pubmed/37176043
http://dx.doi.org/10.3390/ijms24098337

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10179135/
https://www.ncbi.nlm.nih.gov/pubmed/37176043
http://dx.doi.org/10.3390/ijms24098337

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