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Defective Induction of IL-27-Mediated Immunoregulation by Myeloid DCs in Multiple Sclerosis

The purpose of this study was to examine whether myeloid dendritic cells (mDCs) from patients with multiple sclerosis (MS) and healthy controls (HCs) become similarly tolerogenic when exposed to IL-27 as this may represent a potential mechanism of autoimmune dysregulation. Our study focused on natur...

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Detalles Bibliográficos
Autores principales: von Glehn, Felipe, Pochet, Nathalie, Thapa, Bibek, Raheja, Radhika, Mazzola, Maria A., Jangi, Sushrut, Beynon, Vanessa, Huang, Junning, Farias, Alessandro S., Paul, Anu, Santos, Leonilda M. B., Gandhi, Roopali, Murugaiyan, Gopal, Weiner, Howard L., Baecher-Allan, Clare M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10179146/
https://www.ncbi.nlm.nih.gov/pubmed/37175706
http://dx.doi.org/10.3390/ijms24098000