Cargando…
Defective Induction of IL-27-Mediated Immunoregulation by Myeloid DCs in Multiple Sclerosis
The purpose of this study was to examine whether myeloid dendritic cells (mDCs) from patients with multiple sclerosis (MS) and healthy controls (HCs) become similarly tolerogenic when exposed to IL-27 as this may represent a potential mechanism of autoimmune dysregulation. Our study focused on natur...
Autores principales: | von Glehn, Felipe, Pochet, Nathalie, Thapa, Bibek, Raheja, Radhika, Mazzola, Maria A., Jangi, Sushrut, Beynon, Vanessa, Huang, Junning, Farias, Alessandro S., Paul, Anu, Santos, Leonilda M. B., Gandhi, Roopali, Murugaiyan, Gopal, Weiner, Howard L., Baecher-Allan, Clare M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10179146/ https://www.ncbi.nlm.nih.gov/pubmed/37175706 http://dx.doi.org/10.3390/ijms24098000 |
Ejemplares similares
-
microRNA-92a promotes CNS autoimmunity by modulating the regulatory and inflammatory T cell balance
por: Fujiwara, Mai, et al.
Publicado: (2022) -
IL-27 Imparts Immunoregulatory Function to Human NK Cell Subsets
por: Laroni, Alice, et al.
Publicado: (2011) -
Identification of a novel mechanism of action of fingolimod (FTY720) on human effector T cell function through TCF-1 upregulation
por: Mazzola, Maria Antonietta, et al.
Publicado: (2015) -
Smad7 Controls Immunoregulatory PDL2/1-PD1 Signaling in Intestinal Inflammation and Autoimmunity
por: Garo, Lucien P., et al.
Publicado: (2019) -
Comprehensive evaluation of serum microRNAs as biomarkers in multiple sclerosis
por: Regev, Keren, et al.
Publicado: (2016)