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Sex-Dependent Impairment of Endothelium-Dependent Relaxation in Aorta of Mice with Overexpression of Hyaluronan in Tunica Media

Diabetic macroangiopathy is characterized by increased extracellular matrix deposition, including excessive hyaluronan accumulation, vessel thickening and stiffness, and endothelial dysfunction in large arteries. We hypothesized that the overexpression of hyaluronan in the tunica media also led to e...

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Detalles Bibliográficos
Autores principales: Lorentzen, Karen Axelgaard, Hernanz, Raquel, Pinilla, Estéfano, Nyengaard, Jens Randel, Wogensen, Lise, Simonsen, Ulf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10179165/
https://www.ncbi.nlm.nih.gov/pubmed/37176139
http://dx.doi.org/10.3390/ijms24098436