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Tau Lysine Pseudomethylation Regulates Microtubule Binding and Enhances Prion-like Tau Aggregation

Alzheimer’s disease (AD) and frontotemporal dementia (FTD) can be classified as tauopathies, which are a group of neurodegenerative diseases that develop toxic tau aggregates in specific brain regions. These pathological tau inclusions are altered by various post-translational modifications (PTMs) t...

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Detalles Bibliográficos
Autores principales: Xia, Yuxing, Bell, Brach M., Giasson, Benoit I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10179186/
https://www.ncbi.nlm.nih.gov/pubmed/37175990
http://dx.doi.org/10.3390/ijms24098286