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Differential Effects of Overexpression of Wild Type and Kinase-Dead MELK in Fibroblasts and Keratinocytes, Potential Implications for Skin Wound Healing and Cancer

Maternal embryonic leucine-zipper kinase (MELK) plays a significant role in cell cycle progression, mitosis, cell migration, cell renewal, gene expression, embryogenesis, proliferation, apoptosis, and spliceosome assembly. In addition, MELK is known to be overexpressed in multiple types of cancer an...

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Detalles Bibliográficos
Autores principales: Szymański, Łukasz, Lieto, Krystyna, Zdanowski, Robert, Lewicki, Sławomir, Tassan, Jean-Pierre, Kubiak, Jacek Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10179274/
https://www.ncbi.nlm.nih.gov/pubmed/37175795
http://dx.doi.org/10.3390/ijms24098089