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Differential Effects of Overexpression of Wild Type and Kinase-Dead MELK in Fibroblasts and Keratinocytes, Potential Implications for Skin Wound Healing and Cancer
Maternal embryonic leucine-zipper kinase (MELK) plays a significant role in cell cycle progression, mitosis, cell migration, cell renewal, gene expression, embryogenesis, proliferation, apoptosis, and spliceosome assembly. In addition, MELK is known to be overexpressed in multiple types of cancer an...
Autores principales: | Szymański, Łukasz, Lieto, Krystyna, Zdanowski, Robert, Lewicki, Sławomir, Tassan, Jean-Pierre, Kubiak, Jacek Z. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10179274/ https://www.ncbi.nlm.nih.gov/pubmed/37175795 http://dx.doi.org/10.3390/ijms24098089 |
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