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β-Secretase-1: In Silico Drug Reposition for Alzheimer’s Disease

The β-secretase-1 enzyme (BACE-1) performs a key role in the production of beta-Amyloid protein (Aβ), which is associated with the development of Alzheimer’s disease (AD). The inhibition of BACE-1 has been an important pharmacological strategy in the treatment of this neurodegenerative disease. This...

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Detalles Bibliográficos
Autores principales: Galeana-Ascencio, Roberto A., Mendieta, Liliana, Limon, Daniel I., Gnecco, Dino, Terán, Joel L., Orea, María L., Carrasco-Carballo, Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10179340/
https://www.ncbi.nlm.nih.gov/pubmed/37175873
http://dx.doi.org/10.3390/ijms24098164