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Self-Nanoemulsifying Drug Delivery System for Enhanced Bioavailability of Madecassic Acid: In vitro and in vivo Evaluation

PURPOSE: Madecassic acid (MCA) is a natural triterpenoid isolated from centellae herba that has diverse biological effects, such as anti-inflammatory, antioxidant, and anticancer activities. However, the efficacy of MCA is limited by low oral bioavailability caused by its extremely poor aqueous solu...

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Detalles Bibliográficos
Autores principales: Lin, Li, Chen, Qingyong, Dai, Yue, Xia, Yufeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10179365/
https://www.ncbi.nlm.nih.gov/pubmed/37187996
http://dx.doi.org/10.2147/IJN.S408115