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Single-Cell Transcriptomics Reveals Conserved Regulatory Networks in Human and Mouse Interneuron Development

Inhibitory GABAergic interneurons originate in the embryonic medial ganglionic eminence (MGE) and control network activity in the neocortex. Dysfunction of these cells is believed to lead to runaway excitation underlying seizure-based neurological disorders such as epilepsy, autism, and schizophreni...

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Detalles Bibliográficos
Autores principales: Keefe, Francesca, Monzón-Sandoval, Jimena, Rosser, Anne E., Webber, Caleb, Li, Meng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10179417/
https://www.ncbi.nlm.nih.gov/pubmed/37175835
http://dx.doi.org/10.3390/ijms24098122