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The Presence of Periodontitis Exacerbates Non-Alcoholic Fatty Liver Disease via Sphingolipid Metabolism-Associated Insulin Resistance and Hepatic Inflammation in Mice with Metabolic Syndrome

Clinical studies have shown that periodontitis is associated with non-alcoholic fatty liver disease (NAFLD). However, it remains unclear if periodontitis contributes to the progression of NAFLD. In this study, we generated a mouse model with high-fat diet (HFD)-induced metabolic syndrome (MetS) and...

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Detalles Bibliográficos
Autores principales: Lu, Zhongyang, Li, Yanchun, Chowdhury, Nityananda, Yu, Hong, Syn, Wing-Kin, Lopes-Virella, Maria, Yilmaz, Özlem, Huang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10179436/
https://www.ncbi.nlm.nih.gov/pubmed/37176029
http://dx.doi.org/10.3390/ijms24098322