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Enhancement of Sphingomyelinase-Induced Endothelial Nitric Oxide Synthase-Mediated Vasorelaxation in a Murine Model of Type 2 Diabetes

Sphingolipids are important biological mediators both in health and disease. We investigated the vascular effects of enhanced sphingomyelinase (SMase) activity in a mouse model of type 2 diabetes mellitus (T2DM) to gain an understanding of the signaling pathways involved. Myography was used to measu...

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Detalles Bibliográficos
Autores principales: Ruisanchez, Éva, Janovicz, Anna, Panta, Rita Cecília, Kiss, Levente, Párkányi, Adrienn, Straky, Zsuzsa, Korda, Dávid, Liliom, Károly, Tigyi, Gábor, Benyó, Zoltán
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10179569/
https://www.ncbi.nlm.nih.gov/pubmed/37176081
http://dx.doi.org/10.3390/ijms24098375