Spatiotemporal Coordination of RPE Cell Quality by Extracellular Vesicle miR-494-3p Via Competitive Interplays With SIRT3 or PTEN

PURPOSE: To reveal the molecular mechanism underlying degeneration in human retinal pigment epithelial (hRPE) cells with dysfunctional mitochondrial homeostasis. METHODS: The expression of recently identified miR-494-3p in extracellular vesicles (EV) released from induced-pluripotential-stem-cell–de...

Descripción completa

Detalles Bibliográficos
Autores principales: Hamuro, Junji, Yamashita, Tomoko, Otsuki, Yohei, Hiramoto, Nao, Adachi, Mayuka, Miyatani, Takafumi, Tanaka, Hiroshi, Ueno, Morio, Kinoshita, Shigeru, Sotozono, Chie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2023
Materias:
Retinal Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10179576/
https://www.ncbi.nlm.nih.gov/pubmed/37163276
http://dx.doi.org/10.1167/iovs.64.5.9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10179576/
https://www.ncbi.nlm.nih.gov/pubmed/37163276
http://dx.doi.org/10.1167/iovs.64.5.9

Ejemplares similares