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Spatiotemporal Coordination of RPE Cell Quality by Extracellular Vesicle miR-494-3p Via Competitive Interplays With SIRT3 or PTEN

PURPOSE: To reveal the molecular mechanism underlying degeneration in human retinal pigment epithelial (hRPE) cells with dysfunctional mitochondrial homeostasis. METHODS: The expression of recently identified miR-494-3p in extracellular vesicles (EV) released from induced-pluripotential-stem-cell–de...

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Detalles Bibliográficos
Autores principales:	Hamuro, Junji, Yamashita, Tomoko, Otsuki, Yohei, Hiramoto, Nao, Adachi, Mayuka, Miyatani, Takafumi, Tanaka, Hiroshi, Ueno, Morio, Kinoshita, Shigeru, Sotozono, Chie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2023
Materias:	Retinal Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10179576/ https://www.ncbi.nlm.nih.gov/pubmed/37163276 http://dx.doi.org/10.1167/iovs.64.5.9

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