Identification of Catechins’ Binding Sites in Monomeric Aβ(42) through Ensemble Docking and MD Simulations

The assembly of the amyloid-β peptide (Aβ) into toxic oligomers and fibrils is associated with Alzheimer’s disease and dementia. Therefore, disrupting amyloid assembly by direct targeting of the Aβ monomeric form with small molecules or antibodies is a promising therapeutic strategy. However, given...

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Detalles Bibliográficos
Autores principales: Firouzi, Rohoullah, Sowlati-Hashjin, Shahin, Chávez-García, Cecilia, Ashouri, Mitra, Karimi-Jafari, Mohammad Hossein, Karttunen, Mikko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10179585/
https://www.ncbi.nlm.nih.gov/pubmed/37175868
http://dx.doi.org/10.3390/ijms24098161

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10179585/
https://www.ncbi.nlm.nih.gov/pubmed/37175868
http://dx.doi.org/10.3390/ijms24098161

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