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Identification of Catechins’ Binding Sites in Monomeric Aβ(42) through Ensemble Docking and MD Simulations
The assembly of the amyloid-β peptide (Aβ) into toxic oligomers and fibrils is associated with Alzheimer’s disease and dementia. Therefore, disrupting amyloid assembly by direct targeting of the Aβ monomeric form with small molecules or antibodies is a promising therapeutic strategy. However, given...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10179585/ https://www.ncbi.nlm.nih.gov/pubmed/37175868 http://dx.doi.org/10.3390/ijms24098161 |