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Membrane Permeability Is Required for the Vasodilatory Effect of Carbonic Anhydrase Inhibitors in Porcine Retinal Arteries

It has been demonstrated previously that a variety of carbonic anhydrase inhibitors (CAIs) can induce vasodilation in pre-contracted retinal arteriolar segments although with different efficacy and potency. Since the CAIs tested so far are able to permeate cell membranes and inhibit both intracellul...

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Detalles Bibliográficos
Autores principales: Eysteinsson, Thor, García-Llorca, Andrea, Hardarson, Arnar Oessur, Vullo, Daniela, Carta, Fabrizio, Supuran, Claudiu T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10179589/
https://www.ncbi.nlm.nih.gov/pubmed/37175846
http://dx.doi.org/10.3390/ijms24098140