Generation and Characterization of CYP2E1-Overexpressing HepG2 Cells to Study the Role of CYP2E1 in Hepatic Hypoxia-Reoxygenation Injury

The mechanisms of hepatic ischemia/reperfusion (I/R) injury, which occurs during liver transplantation or surgery, are poorly understood. The purpose of the current study was to generate and characterize a HepG2 cell line with a stable overexpression of CYP2E1 to investigate the role of the enzyme i...

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Detalles Bibliográficos
Autores principales: Alwadei, Nouf, Rashid, Mamunur, Chandrashekar, Devaraj Venkatapura, Rahighi, Simin, Totonchy, Jennifer, Sharma, Ajay, Mehvar, Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10179595/
https://www.ncbi.nlm.nih.gov/pubmed/37175827
http://dx.doi.org/10.3390/ijms24098121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10179595/
https://www.ncbi.nlm.nih.gov/pubmed/37175827
http://dx.doi.org/10.3390/ijms24098121

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