GABA(A) Receptor β3 Subunit Mutation N328D Heterozygous Knock-in Mice Have Lennox–Gastaut Syndrome

Lennox–Gastaut Syndrome (LGS) is a developmental and epileptic encephalopathy (DEE) characterized by multiple seizure types, electroencephalogram (EEG) patterns, and cognitive decline. Its etiology has a prominent genetic component, including variants in GABRB3 that encodes the GABA(A) receptor (GAB...

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Detalles Bibliográficos
Autores principales: Nwosu, Gerald Ikemefuna, Shen, Wangzhen, Zavalin, Kirill, Poliquin, Sarah, Randhave, Karishma, Flamm, Carson, Biven, Marshall, Langer, Katherine, Kang, Jing-Qiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10179596/
https://www.ncbi.nlm.nih.gov/pubmed/37176165
http://dx.doi.org/10.3390/ijms24098458

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10179596/
https://www.ncbi.nlm.nih.gov/pubmed/37176165
http://dx.doi.org/10.3390/ijms24098458

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