Hypericin Ameliorates Depression-like Behaviors via Neurotrophin Signaling Pathway Mediating m6A Epitranscriptome Modification

Hypericin, one of the major antidepressant constituents of St. John’s wort, was shown to exert antidepressant effects by affecting cerebral CYP enzymes, serotonin homeostasis, and neuroinflammatory signaling pathways. However, its exact mechanisms are unknown. Previous clinical studies reported that...

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Detalles Bibliográficos
Autores principales: Lei, Chunguang, Li, Ningning, Chen, Jianhua, Wang, Qingzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10179818/
https://www.ncbi.nlm.nih.gov/pubmed/37175269
http://dx.doi.org/10.3390/molecules28093859

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10179818/
https://www.ncbi.nlm.nih.gov/pubmed/37175269
http://dx.doi.org/10.3390/molecules28093859

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