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Big Tau: What We Know, and We Need to Know
Tau is a microtubule-associated protein (MAP) that has multiple isoforms generated by alternative splicing of the MAPT gene at a range of 45–60 kDa [low-molecular-weight (LMW) tau] as well as a unique isoform termed Big tau containing an additional exon 4a encoding a large projecting domain of ∼250...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Society for Neuroscience
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10179842/ https://www.ncbi.nlm.nih.gov/pubmed/37164636 http://dx.doi.org/10.1523/ENEURO.0052-23.2023 |