Chalcone-Derived Lactones: Synthesis, Whole-Cell Biotransformation, and Evaluation of Their Antibacterial and Antifungal Activity

Four compounds with lactone moiety were synthesized from chalcone 1 in three- or four-step synthesis. γ-Bromo-δ-lactone 5 was the only product of bromolactonization of acid 4 whereas bromolactonization of ester 3, apart from lactone 5 also afforded its isomer 6 and two diastereoisomeric δ-hydroxy-γ-...

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Detalles Bibliográficos
Autores principales: Gładkowski, Witold, Siepka, Monika, Żarowska, Barbara, Białońska, Agata, Gawdzik, Barbara, Urbaniak, Mariusz, Wawrzeńczyk, Czesław
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10179843/
https://www.ncbi.nlm.nih.gov/pubmed/37175210
http://dx.doi.org/10.3390/molecules28093800

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10179843/
https://www.ncbi.nlm.nih.gov/pubmed/37175210
http://dx.doi.org/10.3390/molecules28093800

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