Enhanced Solubility and Stability of Aripiprazole in Binary and Ternary Inclusion Complexes Using Hydroxy Propyl Beta Cyclodextrin (HPβCD) and L-Arginine

The low water solubility of an active pharmaceutical ingredient (aripiprazole) is one of the most critical challenges in pharmaceutical research and development. This antipsychotic drug has an inadequate therapeutic impact because of its minimal and idiosyncratic oral bioavailability to treat schizo...

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Detalles Bibliográficos
Autores principales: Awais, Sophia, Farooq, Nouman, Muhammad, Sharmeen Ata, El-Serehy, Hamed A., Ishtiaq, Farrah, Afridi, Mehwish, Ahsan, Hina, Ullah, Amin, Nadeem, Tariq, Sultana, Kishwar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10179852/
https://www.ncbi.nlm.nih.gov/pubmed/37175270
http://dx.doi.org/10.3390/molecules28093860

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10179852/
https://www.ncbi.nlm.nih.gov/pubmed/37175270
http://dx.doi.org/10.3390/molecules28093860

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