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Enhanced Solubility and Stability of Aripiprazole in Binary and Ternary Inclusion Complexes Using Hydroxy Propyl Beta Cyclodextrin (HPβCD) and L-Arginine
The low water solubility of an active pharmaceutical ingredient (aripiprazole) is one of the most critical challenges in pharmaceutical research and development. This antipsychotic drug has an inadequate therapeutic impact because of its minimal and idiosyncratic oral bioavailability to treat schizo...
Autores principales: | Awais, Sophia, Farooq, Nouman, Muhammad, Sharmeen Ata, El-Serehy, Hamed A., Ishtiaq, Farrah, Afridi, Mehwish, Ahsan, Hina, Ullah, Amin, Nadeem, Tariq, Sultana, Kishwar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10179852/ https://www.ncbi.nlm.nih.gov/pubmed/37175270 http://dx.doi.org/10.3390/molecules28093860 |
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