New Hybrid Tetrahydropyrrolo[3,2,1-ij]quinolin-1-ylidene-2-thioxothiazolidin-4-ones as New Inhibitors of Factor Xa and Factor XIa: Design, Synthesis, and In Silico and Experimental Evaluation

Despite extensive research in the field of thrombotic diseases, the prevention of blood clots remains an important area of study. Therefore, the development of new anticoagulant drugs with better therapeutic profiles and fewer side effects to combat thrombus formation is still needed. Herein, we rep...

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Detalles Bibliográficos
Autores principales: Novichikhina, Nadezhda P., Shestakov, Alexander S., Medvedeva, Svetlana M., Lagutina, Anna M., Krysin, Mikhail Yu., Podoplelova, Nadezhda A., Panteleev, Mikhail A., Ilin, Ivan S., Sulimov, Alexey V., Tashchilova, Anna S., Sulimov, Vladimir B., Geronikaki, Athina, Shikhaliev, Khidmet S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10179972/
https://www.ncbi.nlm.nih.gov/pubmed/37175261
http://dx.doi.org/10.3390/molecules28093851

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10179972/
https://www.ncbi.nlm.nih.gov/pubmed/37175261
http://dx.doi.org/10.3390/molecules28093851

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