Chiral Indolizinium Salts Derived from 2-Pyridinecarbaldehyde—First Diastereoselective Syntheses of (−)-1-epi-lentiginosine

The first diastereoselective synthesis of (−)-1-epi-lentiginosine from a common chiral trans-epoxyamide derived from 2-pyridincarbaldehyde is reported. This methodology involves a sequential oxirane ring opening and intramolecular 5-exo-tet cyclization of tosylate trans-epoxyalcohol to afford a dias...

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Detalles Bibliográficos
Autores principales: Rodriguez-Matsui, Hisami, Aparicio, David M., Orea, María L., Juárez, Jorge R., Gómez-Calvario, Victor, Gnecco, Dino, Carrasco-Carballo, Alan, Terán, Joel L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10180032/
https://www.ncbi.nlm.nih.gov/pubmed/37175128
http://dx.doi.org/10.3390/molecules28093719

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10180032/
https://www.ncbi.nlm.nih.gov/pubmed/37175128
http://dx.doi.org/10.3390/molecules28093719

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