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Unlocking the Conformational Changes of P2Y(12): Exploring an Acridinone Compound’s Effect on Receptor Activity and Conformation
The P2Y(12) receptor is an important member of the purinergic receptor family, known for its critical role in platelet activation and thrombosis. In our previously published study, the acridinone analogue NSC618159 was identified as a potent antagonist of P2Y(12). In this work, we investigate the co...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10180088/ https://www.ncbi.nlm.nih.gov/pubmed/37175288 http://dx.doi.org/10.3390/molecules28093878 |