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A Two-Step Synthesis of Unprotected 3-Aminoindoles via Post Functionalization with Nitrostyrene

A novel, low-cost method for the preparation of not easily accessible free 3-aminoindoles has been developed. This approach is based on a well-established reaction between indoles and nitrostyrene in the presence of phosphorous acid, which results in the formation of 4′-phenyl-4′H-spiro[indole-3,5′-...

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Detalles Bibliográficos
Autores principales: Aksenov, Nicolai A., Arutiunov, Nikolai A., Kurenkov, Igor A., Malyuga, Vladimir V., Aksenov, Dmitrii A., Momotova, Daria S., Zatsepilina, Anna M., Chukanova, Elizaveta A., Leontiev, Alexander V., Aksenov, Alexander V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10180116/
https://www.ncbi.nlm.nih.gov/pubmed/37175067
http://dx.doi.org/10.3390/molecules28093657