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Quercetagitrin Inhibits Tau Accumulation and Reverses Neuroinflammation and Cognitive Deficits in P301S-Tau Transgenic Mice

Intracellular tau accumulation is a hallmark pathology of Alzheimer’s disease (AD) and other tauopathies. Tau protein, in the hyperphosphorylated form, is the component of paired helical filaments (PHFs) and neurofibrillary tangles (NFTs) in AD. Blocking tau aggregation and/or phosphorylation is cur...

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Detalles Bibliográficos
Autores principales: Zhong, Suyue, Ye, Jinwang, Deng, Yunsong, Zhang, Mohan, Zou, Miaozhan, Yao, Xuanbao, Xiao, Shifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10180163/
https://www.ncbi.nlm.nih.gov/pubmed/37175376
http://dx.doi.org/10.3390/molecules28093964