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Quercetagitrin Inhibits Tau Accumulation and Reverses Neuroinflammation and Cognitive Deficits in P301S-Tau Transgenic Mice
Intracellular tau accumulation is a hallmark pathology of Alzheimer’s disease (AD) and other tauopathies. Tau protein, in the hyperphosphorylated form, is the component of paired helical filaments (PHFs) and neurofibrillary tangles (NFTs) in AD. Blocking tau aggregation and/or phosphorylation is cur...
Autores principales: | Zhong, Suyue, Ye, Jinwang, Deng, Yunsong, Zhang, Mohan, Zou, Miaozhan, Yao, Xuanbao, Xiao, Shifeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10180163/ https://www.ncbi.nlm.nih.gov/pubmed/37175376 http://dx.doi.org/10.3390/molecules28093964 |
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