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Novel Pyrimidine Derivatives as Antioxidant and Anticancer Agents: Design, Synthesis and Molecular Modeling Studies

The heterocyclic ring system of pyrido [2,3-d]pyrimidines is a privileged scaffold in medicinal chemistry, possessing several biological activities. The synthesis of the pyrimidine derivatives was performed via the condensation of a suitable α,β-unsaturated ketone with 4-amino-6-hydroxy-2-mercaptopy...

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Detalles Bibliográficos
Autores principales: Myriagkou, Malama, Papakonstantinou, Evangelia, Deligiannidou, Georgia-Eirini, Patsilinakos, Alexandros, Kontogiorgis, Christos, Pontiki, Eleni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10180197/
https://www.ncbi.nlm.nih.gov/pubmed/37175322
http://dx.doi.org/10.3390/molecules28093913