Stability Analysis of the Asiatic Acid-COX-2 Complex Using 100 ns Molecular Dynamic Simulations and Its Selectivity against COX-2 as a Potential Anti-Inflammatory Candidate

Asiatic acid, a triterpenoid compound, has been shown to have anti-inflammatory activity through the inhibition of the formation of cyclooxygenase-2 (COX-2) in vitro and in vivo. This study was conducted to determine the binding stability and the inhibitory potential of asiatic acid as an anti-infla...

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Detalles Bibliográficos
Autores principales: Musfiroh, Ida, Kartasasmita, Rahmana E., Ibrahim, Slamet, Muchtaridi, Muchtaridi, Hidayat, Syahrul, Ikram, Nur Kusaira Khairul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10180211/
https://www.ncbi.nlm.nih.gov/pubmed/37175172
http://dx.doi.org/10.3390/molecules28093762

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10180211/
https://www.ncbi.nlm.nih.gov/pubmed/37175172
http://dx.doi.org/10.3390/molecules28093762

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