Three Component One-Pot Synthesis and Antiproliferative Activity of New [1,2,4]Triazolo[4,3-a]pyrimidines

A series of new [1,2,4]triazolo[4,3-a]pyrimidine derivatives was prepared using a one-pot three-component synthesis from 5-amino-1-phenyl-1H-1,2,4-triazoles, aromatic aldehydes and ethyl acetoacetate. The compound structures were confirmed by IR, (1)H-NMR, (13)C-NMR, HRMS and X-ray analyses. The bio...

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Detalles Bibliográficos
Autores principales: Ben Hassen, Manel, Msalbi, Dhouha, Jismy, Badr, Elghali, Fares, Aifa, Sami, Allouchi, Hassan, Abarbri, Mohamed, Chabchoub, Fakher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10180348/
https://www.ncbi.nlm.nih.gov/pubmed/37175327
http://dx.doi.org/10.3390/molecules28093917

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10180348/
https://www.ncbi.nlm.nih.gov/pubmed/37175327
http://dx.doi.org/10.3390/molecules28093917

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