A Novel Paclitaxel Derivative for Triple-Negative Breast Cancer Chemotherapy

Paclitaxel-triethylenetetramine hexaacetic acid conjugate (PTX-TTHA), a novel semi-synthetic taxane, is designed to improve the water solubility and cosolvent toxicity of paclitaxel in several aminopolycarboxylic acid groups. In this study, the in vitro and in vivo antitumor effects and mechanisms o...

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Detalles Bibliográficos
Autores principales: Liu, Yuetong, Hong, Ge, Mao, Lina, Su, Zhe, Liu, Tianjun, Liu, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10180349/
https://www.ncbi.nlm.nih.gov/pubmed/37175072
http://dx.doi.org/10.3390/molecules28093662

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10180349/
https://www.ncbi.nlm.nih.gov/pubmed/37175072
http://dx.doi.org/10.3390/molecules28093662

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