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Thymosin Beta 4 Protects Hippocampal Neuronal Cells against PrP (106–126) via Neurotrophic Factor Signaling

Prion protein peptide (PrP) has demonstrated neurotoxicity in brain cells, resulting in the progression of prion diseases with spongiform degenerative, amyloidogenic, and aggregative properties. Thymosin beta 4 (Tβ(4)) plays a role in the nervous system and may be related to motility, axonal enlarge...

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Detalles Bibliográficos
Autores principales: Kim, Sokho, Choi, Jihye, Kwon, Jungkee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10180446/
https://www.ncbi.nlm.nih.gov/pubmed/37175330
http://dx.doi.org/10.3390/molecules28093920