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Glucosamine-Modified Reduction-Responsive Polymeric Micelles for Liver Cancer Therapy

In this work, glucose transporter-1 (GLUT-1) and glutathione (GSH) over-expression in liver cancer was utilized to design a reduction-responsive and active targeting drug delivery system AG-PEG-SS-PCL (APSP) for the delivery of sorafenib (SF). The SF-APSP micelles were prepared using the thin film h...

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Detalles Bibliográficos
Autores principales: Meng, Lei, Liu, Fangshu, Du, Chenchen, Zhu, Jiaying, Xiong, Qian, Li, Jing, Sun, Weitong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10180462/
https://www.ncbi.nlm.nih.gov/pubmed/37175234
http://dx.doi.org/10.3390/molecules28093824