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Angular Regioselective Synthesis of Varied Functionalized Hexahydro-1,2,4-triazolo[4,3-a]quinazolin-9-ones and Their Antiproliferative Action †

New 2-thioxopyrimidin-4-ones capable of participating in regioselective reactions with functionally diverse hydrazonoyl chlorides towards angular regioisomers, rather than linear ones, were designed and synthesized to form stereoisomeric cis- and trans-hexahydro [1,2,4]triazolo[4,3-a]quinazolin-9-on...

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Detalles Bibliográficos
Autores principales: Said, Awad I., Gajdács, Márió, Zupkó, István, Haukka, Matti, Palkó, Márta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10180492/
https://www.ncbi.nlm.nih.gov/pubmed/37175130
http://dx.doi.org/10.3390/molecules28093718