Adverse Maternal Environments Perturb Hepatic DNA Methylome and Transcriptome Prior to the Adult-Onset Non-Alcoholic Fatty Liver Disease in Mouse Offspring

Exposure to adverse early-life environments (AME) increases the incidence of developing adult-onset non-alcoholic fatty liver disease (NAFLD). DNA methylation has been postulated to link AME and late-onset diseases. This study aimed to investigate whether and to what extent the hepatic DNA methylome...

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Detalles Bibliográficos
Autores principales: Fu, Qi, Cheung, Warren A., Majnik, Amber V., Ke, Xingrao, Pastinen, Tomi, Lane, Robert H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10180730/
https://www.ncbi.nlm.nih.gov/pubmed/37432267
http://dx.doi.org/10.3390/nu15092167

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10180730/
https://www.ncbi.nlm.nih.gov/pubmed/37432267
http://dx.doi.org/10.3390/nu15092167

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