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Adverse Maternal Environments Perturb Hepatic DNA Methylome and Transcriptome Prior to the Adult-Onset Non-Alcoholic Fatty Liver Disease in Mouse Offspring
Exposure to adverse early-life environments (AME) increases the incidence of developing adult-onset non-alcoholic fatty liver disease (NAFLD). DNA methylation has been postulated to link AME and late-onset diseases. This study aimed to investigate whether and to what extent the hepatic DNA methylome...
Autores principales: | Fu, Qi, Cheung, Warren A., Majnik, Amber V., Ke, Xingrao, Pastinen, Tomi, Lane, Robert H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10180730/ https://www.ncbi.nlm.nih.gov/pubmed/37432267 http://dx.doi.org/10.3390/nu15092167 |
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