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FGF21 Depletion Attenuates Colitis through Intestinal Epithelial IL-22-STAT3 Activation in Mice

Fibroblast growth factor 21 (FGF21) is a glucose and lipid metabolic regulator. Recent research revealed that FGF21 was also induced by inflammatory stimuli. Its role in inflammatory bowel disease (IBD) has not been investigated. In this study, an experimental IBD model was established in FGF21 knoc...

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Detalles Bibliográficos
Autores principales: Liu, Liming, Li, Fengyuan, Shao, Tuo, Zhang, Lihua, Lee, Jiyeon, Dryden, Gerald, McClain, Craig J., Zhao, Cuiqing, Feng, Wenke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10181108/
https://www.ncbi.nlm.nih.gov/pubmed/37432218
http://dx.doi.org/10.3390/nu15092086