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Arginine Dysregulation and Myocardial Dysfunction in a Mouse Model and Children with Chronic Kidney Disease

Cardiovascular disease is the leading cause of death in chronic kidney disease (CKD). Arginine, the endogenous precursor for nitric oxide synthesis, is produced in the kidneys. Arginine bioavailability contributes to endothelial and myocardial dysfunction in CKD. Plasma from 129X1/SvJ mice with and...

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Detalles Bibliográficos
Autores principales: Reyes, Loretta Z., Winterberg, Pamela D., George, Roshan Punnoose, Kelleman, Michael, Harris, Frank, Jo, Hanjoong, Brown, Lou Ann S., Morris, Claudia R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10181438/
https://www.ncbi.nlm.nih.gov/pubmed/37432321
http://dx.doi.org/10.3390/nu15092162