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Single-cell transcriptomic atlas of lung microvascular regeneration after targeted endothelial cell ablation

We sought to define the mechanism underlying lung microvascular regeneration in a model of severe acute lung injury (ALI) induced by selective lung endothelial cell ablation. Intratracheal instillation of DT in transgenic mice expressing human diphtheria toxin (DT) receptor targeted to ECs resulted...

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Detalles Bibliográficos
Autores principales: Godoy, Rafael Soares, Cober, Nicholas D, Cook, David P, McCourt, Emma, Deng, Yupu, Wang, Liyuan, Schlosser, Kenny, Rowe, Katelynn, Stewart, Duncan J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10181823/
https://www.ncbi.nlm.nih.gov/pubmed/37078698
http://dx.doi.org/10.7554/eLife.80900