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Bidirectional regulation of postmitotic H3K27me3 distributions underlie cerebellar granule neuron maturation dynamics

The functional maturation of neurons is a prolonged process that extends past the mitotic exit and is mediated by the chromatin-dependent orchestration of gene transcription programs. We find that expression of this maturation gene program in mouse cerebellar granule neurons (CGNs) requires dynamic...

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Detalles Bibliográficos
Autores principales: Ramesh, Vijyendra, Liu, Fang, Minto, Melyssa S, Chan, Urann, West, Anne E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10181825/
https://www.ncbi.nlm.nih.gov/pubmed/37092728
http://dx.doi.org/10.7554/eLife.86273