Cargando…

A TRAF-like E3 ubiquitin ligase TrafE coordinates ESCRT and autophagy in endolysosomal damage response and cell-autonomous immunity to Mycobacterium marinum

Cells are perpetually challenged by pathogens, protein aggregates or chemicals, that induce plasma membrane or endolysosomal compartments damage. This severe stress is recognised and controlled by the endosomal sorting complex required for transport (ESCRT) and the autophagy machineries, which are r...

Descripción completa

Detalles Bibliográficos
Autores principales: Raykov, Lyudmil, Mottet, Manon, Nitschke, Jahn, Soldati, Thierry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10181826/
https://www.ncbi.nlm.nih.gov/pubmed/37070811
http://dx.doi.org/10.7554/eLife.85727