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Aqueous cannabidiol β-cyclodextrin complexed polymeric micelle nasal spray to attenuate in vitro and ex vivo SARS-CoV-2-induced cytokine storms

Cannabidiol (CBD) has a number of biological effects by acting on the cannabinoid receptors CB(1) and CB(2). CBD may be involved in anti-inflammatory processes via CB(1) and CB(2) receptors, resulting in a decrease of pro-inflammatory cytokines. However, CBD's poor aqueous solubility is a major...

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Detalles Bibliográficos
Autores principales: Changsan, Narumon, Sawatdee, Somchai, Suedee, Roongnapa, Chunhachaichana, Charisopon, Srichana, Teerapol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10181874/
https://www.ncbi.nlm.nih.gov/pubmed/37182795
http://dx.doi.org/10.1016/j.ijpharm.2023.123035