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N6-methyladenosine reader YTHDF2 promotes multiple myeloma cell proliferation through EGR1/p21(cip1/waf1)/CDK2-Cyclin E1 axis-mediated cell cycle transition

Multiple myeloma (MM) is the second most common hematological malignancy. N6-methyladenosine (m(6)A) is the most abundant RNA modification. YTH domain-containing family protein 2 (YTHDF2) recognizes m(6)A-cotaining RNAs and accelerates degradation to regulate cancer progression. However, the role of...

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Detalles Bibliográficos
Autores principales: Liu, Rui, Miao, Jiyu, Jia, Yachun, Kong, Guangyao, Hong, Fei, Li, Fangmei, Zhai, Meng, Zhang, Ru, Liu, Jiaxi, Xu, Xuezhu, Wang, Ting, Liu, Hui, Hu, Jinsong, Yang, Yun, He, Aili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10181929/
https://www.ncbi.nlm.nih.gov/pubmed/37012388
http://dx.doi.org/10.1038/s41388-023-02675-w