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N6-methyladenosine reader YTHDF2 promotes multiple myeloma cell proliferation through EGR1/p21(cip1/waf1)/CDK2-Cyclin E1 axis-mediated cell cycle transition
Multiple myeloma (MM) is the second most common hematological malignancy. N6-methyladenosine (m(6)A) is the most abundant RNA modification. YTH domain-containing family protein 2 (YTHDF2) recognizes m(6)A-cotaining RNAs and accelerates degradation to regulate cancer progression. However, the role of...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10181929/ https://www.ncbi.nlm.nih.gov/pubmed/37012388 http://dx.doi.org/10.1038/s41388-023-02675-w |