Biobank-scale inference of ancestral recombination graphs enables genealogical analysis of complex traits

Genome-wide genealogies compactly represent the evolutionary history of a set of genomes and inferring them from genetic data has the potential to facilitate a wide range of analyses. We introduce a method, ARG-Needle, for accurately inferring biobank-scale genealogies from sequencing or genotyping...

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Detalles Bibliográficos
Autores principales: Zhang, Brian C., Biddanda, Arjun, Gunnarsson, Árni Freyr, Cooper, Fergus, Palamara, Pier Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10181934/
https://www.ncbi.nlm.nih.gov/pubmed/37127670
http://dx.doi.org/10.1038/s41588-023-01379-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10181934/
https://www.ncbi.nlm.nih.gov/pubmed/37127670
http://dx.doi.org/10.1038/s41588-023-01379-x

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