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Biobank-scale inference of ancestral recombination graphs enables genealogical analysis of complex traits
Genome-wide genealogies compactly represent the evolutionary history of a set of genomes and inferring them from genetic data has the potential to facilitate a wide range of analyses. We introduce a method, ARG-Needle, for accurately inferring biobank-scale genealogies from sequencing or genotyping...
Autores principales: | Zhang, Brian C., Biddanda, Arjun, Gunnarsson, Árni Freyr, Cooper, Fergus, Palamara, Pier Francesco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10181934/ https://www.ncbi.nlm.nih.gov/pubmed/37127670 http://dx.doi.org/10.1038/s41588-023-01379-x |
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